Esmelira Forte

Composition (per tablet):
• Escitalopram – 10 mg
• Clonazepam – 0.5 mg

Form: Tablet

Description:
Esmelira Forte is a dual-action psychotropic formulation combining Escitalopram, a selective
serotonin reuptake inhibitor (SSRI), and Clonazepam, a benzodiazepine. It is used for the
treatment of moderate to severe anxiety disorders, depression with anxiety features, panic
disorder, and social phobia.
Escitalopram improves mood by enhancing serotonin levels in the brain.
Clonazepam provides rapid relief from acute anxiety and panic symptoms through its
calming, anxiolytic, and sedative effects.

This synergistic combination offers both long-term mood stabilization and immediate anxiety
relief.

Composition

Clonazepam – 0.5 mg

,

Escitalopram – 10 mg

Form

Tablet

Description

Description

Key Benefits:
• Effective in treating anxiety-related depression
• Provides fast control over panic attacks and acute anxiety episodes
• Enhances emotional stability and improves quality of life
• Helps in managing sleep disturbances associated with anxiety

Directions for Use:
Take one tablet daily, preferably in the evening, or as prescribed by your psychiatrist. Do not stop abruptly; tapering is recommended under medical supervision.

Storage:
Store in a cool, dry place below 25°C. Keep away from light and moisture.

Adverse Effects
Esmelira Forte combines an SSRI (Escitalopram) with a benzodiazepine (Clonazepam) to treat depression with anxiety. While effective, this combination may lead to side effects in some individuals.

Major Side Effects (Seek immediate medical attention if these occur):
• Suicidal thoughts or behavior (especially in young adults)
• Severe drowsiness or confusion
• Difficulty breathing or slowed respiration (risk with clonazepam overdose)
• Seizures (rare)
• Serotonin syndrome (fever, agitation, sweating, muscle stiffness, irregular heartbeat)
• Allergic reactions (rash, swelling, difficulty breathing)
• Memory impairment or coordination issues (with prolonged benzodiazepine use)
• Dependence or withdrawal symptoms with abrupt discontinuation

Minor Side Effects (Usually mild and transient):
• Dizziness or light-headedness
• Fatigue or sedation
• Nausea or dry mouth
• Headache
• Sleep disturbances or vivid dreams
• Sexual dysfunction (e.g., decreased libido or delayed ejaculation)
• Increased appetite or weight changes
• Tremors or restlessness (in early weeks)

Precautions:
• May cause drowsiness or sedation—avoid driving or operating heavy machinery
• Risk of dependence with long-term use of Clonazepam
• Should be used cautiously in elderly patients and those with liver or kidney impairment
• Not recommended during pregnancy or breastfeeding unless prescribed
• Avoid alcohol and other CNS depressants while on this medication