SLEPTONIN PLUS®

Therapeutic Class:

• Clonazepam – Benzodiazepine (Anxiolytic, Anticonvulsant)
• Melatonin – Natural sleep hormone (Chronobiotic, Hypnotic)

Primary Indications:

• Insomnia associated with anxiety or stress
• Sleep disturbances in psychiatric disorders
• Jet lag (off-label)
• Delayed Sleep Phase Syndrome (DSPS)
• Adjunct in withdrawal-related sleep issues

This combination offers fast sleep induction (via clonazepam) and circadian rhythm support (via melatonin).

Important Considerations:

• Best for short-term sleep support, especially in anxiety-related insomnia
• Avoid alcohol and CNS depressants
• Melatonin is non-habit forming, unlike clonazepam
• Clonazepam should be tapered off if used beyond a few weeks

Patient-Friendly Summary:

Why they might be used together:

• Melatonin helps your body “know” when it’s bedtime.
• Clonazepam calms the brain, reduces anxiety, and helps you stay asleep.
• Together, they can help in special sleep problems or in anxiety-related insomnia.

Important Safety Tips:

• Take only at bedtime.
• Avoid driving or operating machinery after taking.
• Do not stop clonazepam suddenly without your doctor’s advice.
• Avoid alcohol.