CITIXITE

Mechanism of Action:

Citicoline is a precursor of phosphatidylcholine, a major component of brain cell membranes. It increases choline and cytidine levels in the brain, enhancing the synthesis of:

• Acetylcholine (a key neurotransmitter)
• Phospholipids (for neuronal membrane repair and function)

It also improves cerebral blood flow and mitochondrial function, and has neuroprotective effects after brain injury or stroke.

Indications / Uses:

• Stroke recovery (ischemic stroke, post-stroke rehabilitation)
• Traumatic brain injury (TBI)
• Cognitive disorders (vascular dementia, memory loss, Alzheimer's disease)
• Parkinson’s disease (as an adjunct)
• Glaucoma and amblyopia (neuroprotective in optic nerve diseases)
• ADHD (off-label)

Dosage (Adult):

• Oral: 500–2000 mg per day in divided doses
• IV/IM: 250–1000 mg once or twice daily (typically in hospital setting)
• Dosage may vary depending on condition and severity

Drug Interactions:

• Generally minimal; Citicoline is considered safe to use alongside other CNS drugs
• May enhance effects of levodopa in Parkinson’s disease

Pregnancy & Lactation:

• Category not clearly defined. Use only if clearly needed and prescribed by a doctor.
• Safety in lactation not well established.