Desvaflex-C

Composition (per tablet):
Desvenlafaxine – 50 mg
Clonazepam – 0.5 mg

Form: Tablet

Description:
Desvaflex-C is a combination psychotropic medication containing Desvenlafaxine, a serotonin
norepinephrine reuptake inhibitor (SNRI), and Clonazepam, a benzodiazepine. It is indicated for
the treatment of depression with comorbid anxiety, generalized anxiety disorder (GAD), and
panic disorder, especially in patients requiring both long-term mood stabilization and short-term
anxiety control.
Desvenlafaxine improves mood, motivation, and energy by increasing serotonin and
norepinephrine levels in the brain.
Clonazepam provides rapid relief from anxiety, restlessness, and panic attacks through its
calming, anxiolytic, and anticonvulsant effects.

Composition

Clonazepam – 0.5 mg

,

Desvenlafaxine – 50 mg

Form

Tablet

Description

Description

Key Benefits:
• Dual-action formula for managing depression with anxiety features
• Immediate relief from acute anxiety, restlessness, and panic
• Improves emotional balance, sleep quality, and concentration
• Enhances compliance by reducing early treatment-related anxiety symptoms

Directions for Use:
Take one tablet daily or as prescribed by your psychiatrist. Take at the same time each day with or without food. Do not discontinue suddenly without medical advice.

Storage:
Store in a cool, dry place below 25°C. Protect from light and moisture.

Adverse Effects
Desvaflex-C combines an SNRI antidepressant (Desvenlafaxine) with a benzodiazepine (Clonazepam) to treat depression and anxiety disorders. While effective, the combination may lead
to side effects, particularly during early treatment or dose changes.

Major Side Effects (Seek immediate medical attention if any occur):
• Suicidal thoughts or behavior (especially in younger patients)
• Difficulty breathing or slowed respiration (linked to clonazepam)
• Seizures or severe drowsiness
• Serotonin syndrome (agitation, hallucinations, rapid heartbeat, muscle stiffness, fever)
• Allergic reactions (rash, swelling of face/tongue, trouble breathing)
• Liver dysfunction (jaundice, dark urine, persistent nausea)
• Dependency or withdrawal symptoms with abrupt discontinuation (clonazepam-related)
• Abnormal bleeding or bruising

Minor Side Effects (Usually mild and self-limiting):
• Drowsiness or sedation
• Dizziness or light-headedness
• Headache
• Dry mouth or metallic taste
• Nausea or constipation
• Blurred vision or coordination issues
• Sexual dysfunction (reduced libido or delayed ejaculation)
• Mild weight gain or appetite changes
• Fatigue or weakness

Precautions:
• Clonazepam may cause drowsiness and should not be combined with alcohol or CNS depressants
• Risk of dependency with long-term benzodiazepine use—periodic reassessment recommended
• Tapering required when discontinuing
• Use with caution in elderly patients or those with liver, kidney, or respiratory conditions
• Not recommended during pregnancy or breastfeeding unless deemed essential by the physician.