IRITICALM

Mechanism of Action:

• Chlordiazepoxide: A benzodiazepine with anxiolytic and sedative effects. Reduces stress-related GI symptoms by calming the central nervous system.
• Clidinium Bromide: An anticholinergic that reduces GI motility and secretions, helping to relieve cramps, spasms, and abdominal pain.

 Usual Adult Dosage:

One capsule/tablet, taken 2 to 4 times daily before meals and at bedtime.
(Doses may vary depending on brand and patient tolerance.)

Indications:

• Irritable Bowel Syndrome (IBS)
• Peptic ulcer disease (as adjunct)
• Functional gastrointestinal disorders (e.g., abdominal cramps, bloating)
• Acute enterocolitis

Common Side Effects:

• Dry mouth
• Drowsiness or sedation
• Urinary retention (especially in elderly patients)

Use With Caution In:

• Elderly patients (risk of sedation and confusion)
• Glaucoma
• Prostatic hypertrophy
• Severe hepatic or renal impairment
• Pregnant or breastfeeding women (Category D for chlordiazepoxide)